The Crown Prince That Sells Medicine

The Crown Prince That Sells Medicine Chapter 327

Episode 327 Even a speck of dust squirms when you step on it. (2)

Type 1 diabetes (type 1 diabetes Insulin dependent diabetes mellitus: IDDM). E10 in the International Classification of Diseases (ICD-10).

An incurable or incurable disease called insulin-dependent diabetes.

This is dangerous.

It’s not just diabetes.

Everything from the cause of the disease to the risks is completely different from type 2 diabetes, a common adult disease caused by poor eating habits or obesity. No, it’s just a completely different disease.

“So, if it’s according to what you said…”

“Hmm. There is an organ in your body called the pancreas, and the beta cells that produce insulin in the pancreas are being destroyed. “Actively even at this moment.”

“Beta cells…”

Damian muttered quietly. For some reason, I keep feeling like my lips are getting dry. I was actually thirsty. I had no strength in my whole body. Is that why? I couldn’t readily understand the crown prince’s words.

“Why is it being destroyed?”

“Normally, the body’s immune system is messed up. “The white blood cells that are supposed to defend the body from external enemies recognize beta cells as enemies.”

“Are you attacking me?”

“uh. It’s a team kill. “That’s a typical symptom of an autoimmune disease.”

Rachiel nodded.

Suddenly, an incident from three days ago came to mind. It was a normally busy day. It was the end of an extremely routine day, where I helped the princess with her rehabilitation treatment, treated general patients, and ate a meal in my spare time.

At the end, I went for a walk to catch my breath. It was an extremely pleasant evening walking around and talking about various things with Damien.

And Damian collapsed.

He just collapsed without any warning or sign. At first I thought it was a joke. It wasn’t. No matter how much I shook, I didn’t know if I would wake up. The guards flocked to the sudden shout from this side. In the meantime, I took a pulse. Thanks to you, I realized it.

‘My blood sugar… was skyrocketing.’

I had to believe my eyes while looking at the comprehensive medical checkup sheet. The blood sugar level was far above the dangerous level. The cause was destruction of beta cells in the pancreatic islets of Langerhans. This meant that the production of insulin, which the body naturally produces, was almost completely cut off.

“That’s why. “Insulin is a hormone that acts as a kind of intermediary in the body.”

“Intermediary… role?”

“uh. “A guy who arranges blind dates so that the body can use the nutrients contained in the blood.”

“Then…”

“That’s right. If your body can’t produce insulin, it means it can’t use any of the nutrients in your blood. Because there is no insulin. Because I can’t arrange a blind date. Even if there are excess nutrients, none of them can be used by the muscles or body organs and they are all lost. “With urine.”

It is true.

Nutrients that remain in the blood because they cannot be used.

That is the reality of high blood sugar.

What if type 2 diabetes, which is common, even if there is insulin, the body becomes insensitive to insulin, so the eye for blind dates becomes too high, and even when the arranger introduces you, you are so indifferent that you don’t use much energy and your blood sugar rises?

Type 1 diabetes is a situation where blind date arrangers have become completely extinct.

That’s why it’s more serious.

“Then your highness? “Isn’t it okay to just get that insulin?”

“It’s easier said than done.”

Rachiel smiled bitterly.

“But I have to try.”

If you don’t do it, it’s over.

The time given to Damian is probably about a month. What if I can’t administer insulin beyond that time? I’m going to die. Probably not, 100% sure. You will suffer a rapid death from diabetic ketoacidosis and various acute complications.

Then… the Demon King will wake up in Damian’s body.

‘shit.’

Rakiel gritted his teeth inwardly. And I checked Damian’s pulse to confirm.

‘Jinmaek.’

Ding dong!

[Begin taking pulse.]

[Scanning.]

[3… 2… 1…]

[The pulse results have been received.]

[Please check the

below.]

The results have been returned.

The content was as expected.

[Comprehensive medical checkup]

[Test of examination: Damian Cayenne]

[Race: Human(+?)]

[Gender: Male]

[Age: 3913]

[Height: 186.6 Cm]

[Weight: 71.1 Kg]

[Blood type: He+ D]

Weight This has decreased a lot.

I used to weigh around 79 kilograms, but I lost almost 8 kilograms in a short period of time. But there was a more serious part.

[Comprehensive opinion: The body is in extremely critical condition in all categories. Typical type 1 diabetes is detected. Blood sugar homeostasis collapsed due to lack of insulin secretion due to destruction of pancreatic beta cells. Rapid insulin administration is required. This is mandatory, not recommended, and if it is violated, life cannot be guaranteed.]

“….”

I checked again just in case, but the results were still grim. While examining many patients, this is the first time I have seen comprehensive findings in such a serious tone.

But Rakiel did not just despair. I can’t give up. insulin? If you can’t get it, just make it. Of course, it would be impossible to produce it with a perfect process like in a modern factory, but that does not mean there is no way.

‘With 1921 Toronto-style folk medicine(?) that keeps tradition alive!’

Suddenly, an actual example from history came to mind.

Was it almost exactly 100 years ago? At the time, type 1 diabetes was a disease that would kill you if you got it. Even now, it is difficult to live without insulin, but at the time, insulin had not been discovered at all.

The same was true for a 14-year-old boy named Leonardo Thompson, who was hospitalized at a university hospital in Toronto, Canada at that time. Leonardo was diagnosed with diabetes in 1919, and by 1921, almost all of his hair had fallen out and only his bones and skin remained, waiting for the day to die.

Did you say that a rope of salvation came down to the boy at that time?

‘A man named Banting and his assistant at the University of Toronto made an amazing discovery. When a dog’s pancreas extract was injected into another experimental dog, it was discovered that blood sugar levels continued to drop.’

Rakiel searched for memories.

What was the method Banting and his assistant used at that time?

okay.

It occurred to me.

“anise?”

“Your Highness?”

“Let’s kill a cow right now.”

“…yes? no way?”

The head nurse opened her eyes wide.

Rachiel hastily corrected the misunderstanding(?).

“Not Urus, just bull. “Please tell the chamberlain to get one as healthy as possible.”

“Oh, I understand, Your Highness.”

Anis came out of the hospital room.

Rakiel spoke to Damian.

“I’ll make you some insulin, so just hold on a little longer.”

Damian had no answer. Is it because I lost energy? He seemed to have fallen asleep quickly.

It was from then on.

Rakiel accelerated the production of traditional(?) insulin.

First, I killed a bull. The pancreas was removed and placed in acidic alcohol. Up to this point, we have referred to Banting’s method. A biochemist named James Collip later added a supplementary method.

The concentration of alcohol in which the pancreas is soaked was increased. In that state, the whole pancreas and alcohol were finely ground.

‘James Collip discovered that when the concentration of alcohol is increased like this, all unnecessary fat, protein, and salt sinks like dry matter.’

So I did that.

Of course, it wasn’t easy at first.

It took several trials and errors. It was because of the difference between hearing about it and actually doing it. Mistakes and failures were repeated and piled up one after another.

But I didn’t give up.

I grinded steadily.

Centrifugation was performed.

Head nurse Anis had a great contribution there.

“anise?”

“Yes, Your Highness.”

“Can you hold this and spin it around while transformed?”

“yes?”

“As powerful and fast as possible. “Don’t stop or miss, just 10 minutes.”

“All right.”

I handed Anis a container containing a mixture of ground up pancreas and high-concentration alcohol. Anise received the courage and transformed into werewolf mode. And started spinning furiously.

“Crumbling! Wow!”

A dehydrator that runs powerfully with a wild roar, no, it’s a natural centrifuge! Thanks to this, after 10 minutes, the solution in the container was divided exactly in half.

Useless ingredients such as protein and fat precipitated and sank to the bottom. On the other hand, only the necessary active ingredients such as insulin were dissolved in alcohol and floated around.

In this way, impurities were first filtered out.

Of course, it didn’t end here.

The alcohol concentration of the remaining solution was further increased. When the alcohol was concentrated to over 90%, the necessary pancreatic extract finally separated from the solution and began to precipitate downward.

“Then Anise?”

“Can I transform again and turn it around?”

“huh. 15 minutes this time. Thank you in advance.”

“…Whoa whoa! “Crumbling!”

The Werewolf-type centrifuge is running powerfully again! Pure pancreatic extract finally obtained!

The next step was sterilization.

‘The method is filter sterilization.’

The pancreatic extract could not be heated carelessly. If that happens, all the ingredients will deteriorate. do not do that. So we used a traditional yet simple method. The method was to filter the extract through several layers of beeswax paper.

‘This looks simple, but it’s actually very effective.’

The principle was very simple. The principle was that bacteria remaining in the extract could not pass through the fine cracks of the beeswax paper. In other words, it is a method of filtering out germs using a very fine sieve.

The extract was filtered three times through a total of 7 layers of beeswax paper. Finally, a nearly sterile final extract was obtained. It was a natural secretion of insulin made from the cow’s pancreas.

However, insulin could not be used on Damian right away. Damian was extremely weak. What if any of the ingredients in insulin cause a rejection reaction? A fatal situation could have occurred immediately.

So, I started with an experiment.

The test subject was Rachiel herself.

He injected a small amount of insulin into his forearm. And I waited, checked, and observed. In any case, it might cause rejection or inflammation in the human body.

Fortunately there were very few.

The injection site was only slightly red, like a mosquito bite. Except for a mild allergic reaction, no major rejection or side effects were observed.

It was as soon as the confirmation was completed.

Rachiel hurried to prepare the injection. I rushed to Damien’s hospital room with insulin. Damian happened to be awake in his hospital bed.

“Whoa! “Are you ready?”

“…You’re saying you’re going to inject that into me, right?”

“uh. Ah yes. how?”

“I heard it from the nurses. Your Majesty has been sweating for two days grinding, concentrating, and filtering something. And that was probably the time to make the insulin you mentioned earlier.”

“that’s right. And like this.”

“Are you successful?”

“So it’s just that.”

“….”

“what. why. what. “Why are you looking at me like that?”

“For some reason, Your Majesty seemed much more nervous than I was about getting the injection.”

“nervous? I?”

“yes. “You’re smiling with your face, but not with your hands.”

“….”

Damian’s simple point.

Rakiel finally realized.

The hand holding the syringe was shaking.

‘Whoa.’

Damian was right.

Honestly, I was very nervous.

What if the extract doesn’t work? What if unexpected fatal side effects occur? I was extremely worried.

Damian, on the other hand, just laughed.

“It’s okay, Your Highness. “You can do it.”

“…what. “What if you support me after getting the injection?”

“Because when I die, it’s over.”

“….”

“If I die and my body is taken over by that guy, won’t your highness be the only one to walk this difficult path from then on?”

“aha. “It’ll be easier since you’re dead anyway, right?”

“You understand quickly.”

“It makes me want to hit you.”

“Are you going to assault the patient?”

“….”

“Please let me go, injection.”

“I figured it out later.”

A smile that finally comes out. Thanks to Damian’s shameless response, the tension eased a bit. Anyway, we ended up here. Nothing will get better if you hesitate. I took a deep breath. I stared at the solution in the syringe as if to inspire confidence.

‘The first dose is 5ml.’

The syringe was moved.

stabbed Injected.

It was that moment.

– A dust from another dimension. dare.

“…!”

A huge voice rang in my head. An overwhelming feeling that can be felt in the soul. My vision became dark. The world was dyed in darkness. Is this a hallucination? no. I have experienced it. From Kranos. In the collapsing canyon. While trying to stop the being that was trying to awaken inside Damian.

‘Demon King…?’

It’s him.

The moment of realization.

As if they were trying to interfere with the treatment.

An overwhelming, mythical presence weighed down my soul.